Can the Apple M1 (16GB) run Mistral Nemo 12B?

Yes
QuantQ5_K_MVery good
Memory10.6 GBof 10.7 GB
Speed~5tokens/s

Yes. The Apple M1 (16GB) can run Mistral Nemo 12B fully in unified memory at Q5_K_M (very good), using about 10.6 GB of the 10.7 GB available, at roughly 5 tokens/second.

Try other context lengths in the calculator →

Memory needed by quantization

At 8,192 tokens of context. macOS lets the GPU use about 10.7 GB of the 16 GB unified memory by default.

QuantQualityMemoryFits?Speed
FP16Full quality26.3 GBToo big—
Q8_0Near-lossless14.9 GBToo big—
Q6_KExcellent11.9 GBToo big—
Q5_K_MVery good10.6 GBFits~5 tok/s
Q4_K_MGood, most popular9.3 GBFits~6 tok/s
Q3_K_MNoticeably degraded7.9 GBFits~7 tok/s
Q2_KHeavily degraded6.5 GBFits~9 tok/s

How to run Mistral Nemo 12B on the Apple M1 (16GB)

With Ollama installed, one command downloads and starts it:

ollama run mistral-nemo:12b

Ollama's default download is Q4_K_M (about 9.3 GB here). You have room for Q5_K_M, which is very good: pick that GGUF in LM Studio or from Hugging Face.

GPUs that run Mistral Nemo 12B comfortably

Models that run well on the Apple M1 (16GB)

Run it in the cloud

Don't want to buy hardware? Run Mistral Nemo 12B on a rented GPU today.

Rent a cloud GPU by the hour. No upfront cost, cancel any time.