Can the NVIDIA RTX 4060 run Qwen2.5 72B?

RTX 4060 × Qwen2.5 72B8K context
NoDoes not fit in memory
Memory at Q4_K_M47.4 GB of 8 GB
Weights 44.1 GBKV cache 2.7 GBRuntime 0.6 GB
  1. FP16
  2. Q8_0
  3. Q6_K
  4. Q5_K_M
  5. Q4_K_M
  6. Q3_K_M
  7. Q2_K

No. Even at Q4_K_M, Qwen2.5 72B needs about 47.4 GB, but the NVIDIA RTX 4060 has 8 GB usable. You could offload some layers to system RAM, but it will be very slow.

Run it on a rented GPU

On a cloud GPU with enough memory, the same command you'd use locally works:

ollama run qwen2.5:72b

At Q4_K_M it needs about 47.4 GB, so pick a GPU with at least 48 GB.

New to this? Step-by-step setup for the RTX 4060

Run it in the cloud

Too big for the NVIDIA RTX 4060? Run Qwen2.5 72B on a rented GPU instead.

Rent a cloud GPU by the hour. No upfront cost, stop any time. Not sure whether to rent or buy? Compare the cost.

Memory needed by quantization

At 8,192 tokens of context. The black line marks the 8 GB the NVIDIA RTX 4060 can use.

QuantQualityMemoryFits?Speed
FP16Full quality148.7 GBToo big—
Q8_0Near-lossless80.5 GBToo big—
Q6_KExcellent62.9 GBToo big—
Q5_K_MVery good55 GBToo big—
Q4_K_MGood, most popular47.4 GBToo big—
Q3_K_MNoticeably degraded38.8 GBToo big—
Q2_KHeavily degraded30.5 GBToo big—

Frequently asked questions

Can NVIDIA RTX 4060 run Qwen2.5 72B?

No. Even at Q4_K_M, Qwen2.5 72B needs about 47.4 GB, but the NVIDIA RTX 4060 has 8 GB usable. You could offload some layers to system RAM, but it will be very slow.

How much VRAM does Qwen2.5 72B need?

About 47.4 GB at Q4_K_M with 8,192 tokens of context, and about 148.7 GB at full FP16 precision.

How fast is Qwen2.5 72B on the NVIDIA RTX 4060?

It does not fit in the NVIDIA RTX 4060's memory, so most layers would run from system RAM and generation would be very slow.